Shareen is Professor and Honorary Consultant in Diabetes at the University of Edinburgh and NHS Lothian, Lead Physician for the Islet Transplant Programme in Scotland and Visiting Professor for the Islet Transplant Programme in Edmonton, Canada. She conducts clinical and laboratory based research. She is interested in the progression of diabetes related complications in people with type 1 diabetes in relation to different treatments and the mechanisms behind insulin and glucagon secretion. She also investigates the mechanisms behind islet-graft loss and aims to reduce islet loss and improve islets’ engraftment in vivo using innovative therapies including cell and gene-therapy based approaches.