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Our researchers are working on different ways to develop a cure for type 1 diabetes - from growing insulin-producing beta cells in labs to hacking the immune system.
Learn about the technologies that can deliver insulin automatically when needed. And discover the next generation of insulins that are currently being developed.
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The announcement is the biggest treatment breakthrough for type 1 diabetes since the discovery of insulin.
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Home > About JDRF & our impact > Our research
One day, we will create a world without type 1 diabetes. Until that day, your support is vital for our international research to cure, treat and prevent type 1.
We fund international research that will cure, treat and prevent type 1 diabetes and its complications. We focus on investing in research that will transform the lives of people with type 1 diabetes – improving treatments today until we find a cure.
Over 400 active research studies are being funded by JDRF around the world
JDRF-funded research is currently taking place in 21 countries
At any one time, JDRF is funding around 20 research projects in the UK
Discover how we’re working to cure, treat and prevent type 1 diabetes
Our researchers are working on lots of different ways to develop a cure for type 1 diabetes, from growing insulin-producing beta cells in labs to hacking the immune system to stop it attacking beta cells.
We’re improving lives by developing new ways to treat type 1 diabetes, until we find a cure. Our treatment research includes advancing technologies to help people with type 1 manage their blood glucose levels, creating new and improved types of insulin, and tackling diabetes complications.
Our prevention research aims to fix the problems with the immune system that lie at the heart of the condition. We’re also supporting screening projects to find people in the earliest stages of developing type 1 and delay their need for insulin injections.
The US FDA recently approved a drug that can delay the onset of type 1 diabetes for up to three years, called teplizumab. This success wouldn’t have happened without 30 years of JDRF funding research.
Since 2006, we have funded research to develop and test hybrid closed loop (HCL) technology, which links people's insulin pump to their continuous glucose monitor. Now, HCL is set to become available to many people on the NHS.
For over 20 years, we funded Professor Doug Melton to grow stem cells into insulin-producing beta cells. Doug now works at Vertex Pharmaceuticals, who are running a clinical trial transplanting Doug’s lab-grown beta cells into people with type 1.
Daniel Doherty’s research project aims to make islet transplants last longer and work better to benefit more people with type 1.
Lead researcher, Kourosh, says his study has the potential to transform our understanding of diabetes.
Dr Leslie Johnson will explore whether a collaborative care model that is effective for type 2 diabetes can be adapted for people with type 1.
Dr Chloe Rackham is investigating how supportive cells called mesenchymal stem cells may help protect people from developing type 1.
Dr Ify Mordi is an expert in heart disease and diabetes at the University of Dundee. We are funding Ify to run the first clinical trial of the drug sotagliflozin in people living with type 1 diabetes and heart failure.
In his JDRF-funded project, Dr Richard Oram is developing a type 1 diabetes risk score to predict who will develop type 1 diabetes in the future. The research Richard and his team at the University of Exeter are doing will help how we screen people for type 1.
We are funding Professor Timothy Tree and his team at King’s College London to support clinical trials of ustekinumab in young people recently diagnosed with type 1 diabetes. The team is analysing blood samples from people taking part in the clinical trials USTEKID and UST1D2.
The Human Islet Isolation Facility provides researchers with pancreas samples from donors with and without diabetes. We have been funding the centre since 2009. The current funding is for Professor Paul Johnson and his team to continue to run the Human Islet Isolation Facility at the University of Oxford. Their goal is to supply 1 million pancreatic islets to research each year.
Learn about clinical trials, how to get involved in the different kinds of type 1 diabetes research and view current opportunities.
Dr Rachel Besser, Consultant and Research Lead at Oxfordshire Children’s Diabetes Service, and researcher at the University of Oxford, on how teplizumab being approved in the US benefits children in the UK.
Globally, we have invested over £2 billion in research to date and are currently funding more than 400 research projects and 19 clinical trials. JDRF has several funding opportunities available that address our mission to cure, treat and prevent type 1 diabetes.
The research, which was co-funded by JDRF, reveals that drugs that target the immune system offer very effective and rapid improvements in stabilising blood sugar levels, often within just three months.
The new JDRF-funded clinical trial called SOPHIST will test a drug to help people with type 1 diabetes and heart failure.
Results from a clinical trial called the PROTECT study show that teplizumab can preserve beta cell function in children and adolescents newly diagnosed with type 1 diabetes.
We work with researchers and partner organisations to make sure we can improve life with type 1 diabetes as quickly as possible. Learn about the research we do in partnership with other organisations.
Discover how we work with other organisations to help us make every penny we receive from our amazing supporters go even further to help people with type 1.
Learn about how we're partnering with other autoimmune research funders, pooling our resources to help prevent and cure a range of autoimmune conditions, including type 1 diabetes.
The Type 1 Diabetes Grand Challenge is a partnership between the Steve Morgan Foundation, Diabetes UK and JDRF. We are united by our ambition to cure type 1 diabetes.
Don’t miss out on the latest research, inspiring stories, tech news, upcoming events, and handy information on living well with type 1. Join us now and receive it all straight to your inbox.
It’s thanks to your dedication that we have funded great progress in type 1 cure, treatment and prevention research. Help us to continue our vital research.