Skip to main content

JDRF is undergoing a transformation.
We are becoming Breakthrough T1D in October.

breakthrought1d logo

Our research

One day, we will create a world without type 1 diabetes. Until that day, your support is vital for our international research to cure, treat and prevent type 1.

A type 1 diabetes researcher on Dr Rocio Sancho's team, working in the lab

What research does JDRF fund?

We fund international research that will cure, treat and prevent type 1 diabetes and its complications. We focus on investing in research that will transform the lives of people with type 1 diabetes – improving treatments today until we find a cure.

400+

Over 400 active research studies are being funded by JDRF around the world

21

JDRF-funded research is currently taking place in 21 countries

20

At any one time, JDRF is funding around 20 research projects in the UK

Learn about our research

Discover how we’re working to cure, treat and prevent type 1 diabetes

Recent research highlights

Read more
A girl with type 1 diabetes after a teplizumab injection
Treatments

Teplizumab: The world’s first type 1 diabetes disease-modifying drug approved in the US

The US FDA recently approved a drug that can delay the onset of type 1 diabetes for up to three years, called teplizumab. This success wouldn’t have happened without 30 years of JDRF funding research.

Read more
Illustration of the hybrid closed loop technology system, funded as part of treatment research for type 1 diabetes by JDRF.
Treatments

Hybrid closed loop to be recommended for over 100,000 people with type 1 diabetes

Since 2006, we have funded research to develop and test hybrid closed loop (HCL) technology, which links people's insulin pump to their continuous glucose monitor. Now, HCL is set to become available to many people on the NHS.

Read more
Microscopic view of stem cells
Cure

Promising stem cell therapy for type 1 given green light to progress

For over 20 years, we funded Professor Doug Melton to grow stem cells into insulin-producing beta cells. Doug now works at Vertex Pharmaceuticals, who are running a clinical trial transplanting Doug’s lab-grown beta cells into people with type 1.

Latest research projects

Read more
Shareen Forbes
Cure Treatment

Boosting islet survival after transplantation using immune cells

Professor Shareen Forbes is investigating whether giving certain immune cells with islet transplants can help the islets survive in the recipient and reduce the need for immune-suppressing drugs.

Read more
Professor Yanick Crow
Prevention

Understanding the role of interferon in autoimmunity

Connect Immune Research has launched a first-of-its-kind research project to confront the UK’s high prevalence of autoimmune conditions.

Read more
Professor Alexander Midas
Treatment

Testing a new treatment to lower blood glucose in people with type 1

Professor Alexander Miras is investigating whether alpha-melanocyte stimulatory hormone (α-MSH) can lower blood sugar levels in people with type 1.

Read more
Daniel Doherty
Treatment

Improving islet transplants to treat type 1 diabetes

Daniel Doherty’s research project aims to make islet transplants last longer and work better to benefit more people with type 1.

Read more
Professor Kourosh Saeb-Parsy
Prevention

Analysing pancreas biology to enable early detection of type 1 diabetes

Lead researcher, Kourosh, says his study has the potential to transform our understanding of diabetes.

Read more
Dr Leslie Johnson
Treatment

Improving mental health and blood glucose management in people with type 1 diabetes and depression

Dr Leslie Johnson will explore whether a collaborative care model that is effective for type 2 diabetes can be adapted for people with type 1.

Read more
Dr Chloe Rackham
Treatment

Can islet helper cells in the pancreas treat type 1 diabetes?

Dr Chloe Rackham is investigating how supportive cells called mesenchymal stem cells may help protect people from developing type 1.

Read more
Dr Ify Mordi, lead type 1 diabetes researcher
Complications Treatment

The SOPHIST Trial: sotagliflozin for people with type 1 and heart failure

Dr Ify Mordi is an expert in heart disease and diabetes at the University of Dundee. We are funding Ify to run the first clinical trial of the drug sotagliflozin in people living with type 1 diabetes and heart failure.

Stories from the lab

Latest research news

Read more
A row of vials of clear liquid with black lids. A blue gloved hand is pinching the top of the closest vial as if to pick it up.
Research
13 May 2024

Novel insulin being developed to enable implantable insulin pumps

Medtronic Diabetes have announced they are funding the biopharmaceutical company Arecor Therapeutics to develop a novel, highly concentrated, thermostable insulin, which will be specialised for use in implantable insulin pumps.

Read more
Professor Colin Dayan at Cardiff University, working on immunotherapy for type 1 diabetes cure research
Research
18 April 2024

Professor Colin Dayan presented with the 2023 JDRF Rumbough Award 

The award recognises Professor Dayan’s remarkable accomplishments in type 1 diabetes research.

Read more
Two young children sat on the floor hugging each other.
Research
18 April 2024

Genetically unique siblings reveal new treatment target for type 1 diabetes

Two siblings who have unique changes in a key gene have given researchers new insights that could help lead to innovative new treatments in type 1 diabetes.

Read more
A female doctor works at a laptop on a table. She is wearing a shirt and glasses with a stethoscope around her neck.
Prevention research
17 April 2024

New international medical code launches for presymptomatic type 1 diabetes

JDRF-funded researchers from the University of Birmingham have joined forces with NHS England to develop a diagnostic code for use on electronic medical records of people in the earliest stages of type 1 diabetes, allowing them to receive better, more timely healthcare and access to emerging treatments.

Our research partnerships

We work with researchers and partner organisations to make sure we can improve life with type 1 diabetes as quickly as possible. Learn about the research we do in partnership with other organisations.

Read more

Our research partnerships

Discover how we work with other organisations to help us make every penny we receive from our amazing supporters go even further to help people with type 1.

Read more
Connect Immune Research partnership logo

Connect Immune Research

Learn about how we're partnering with other autoimmune research funders, pooling our resources to help prevent and cure a range of autoimmune conditions, including type 1 diabetes.

Read more
A woman type 1 diabetes scientist in a laboratory

The Type 1 Diabetes Grand Challenge

The Type 1 Diabetes Grand Challenge is a partnership between the Steve Morgan Foundation, Diabetes UK and JDRF. We are united by our ambition to cure type 1 diabetes.