Scientific title: Tolerizing insulin-reactive CD8 T cells in type 1 diabetes
Principal Investigator: Dr Terri Thayer
Institution: Cardiff University
Project duration: 01/06/2014 – 31/10/2019
Objective: Dr Thayer is studying a particular type of immune system cell that, in type 1 diabetes, can go on to attack the insulin-producing cells of the pancreas. If she can learn what happens to cause this behaviour (or what does not happen to prevent it), this knowledge could help develop a way to ‘re-educate’ the immune cells in people with type 1, potentially halting the attack on the pancreas. In particular, Dr Thayer is looking at exposing the cells to insulin to make them more tolerant of it and of the cells that make it.
Categories: Prevent, Cure, Postdoctoral Fellowship, Immune Therapies