JDRF, the type 1 diabetes charityResearch ProjectsGlucose-responsive ‘smart’ insulin

Glucose-responsive ‘smart’ insulin

John Fossey 2Scientific title: Glucose-Responsive Insulin Therapy (GRIT)
Principal Investigator: Professor John Fossey
Institution: University of Birmingham
Project duration: 01/12/2016 – 31/12/2019

Objective: Glucose responsive insulin is a type of injectable insulin that responds to glucose levels in the blood.

Prof Fossey’s laboratory based project involves creating balls of a special gel which contain pockets of insulin, and which dissolve in high concentrations of glucose. The long term goal is that these balls could be injected into the blood, and, a bit like a bath bomb in water, would break up in the presence of high glucose levels, releasing the pockets of insulin. If the project is successful, the work could move to pre-clinical – animal model – testing.

Categories: Treat, Glucose-responsive insulin

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