Can a genetic fingerprint predict diabetic retinopathy? – COMPLETED

Professor Manuel Mayr
Professor Manuel Mayr

Scientific title: Endothelial microRNA 126 as biomarker candidate for diabetic retinopathy
Principal Investigator: 
Professor Manuel Mayr
Institution: King’s College London
Project duration: 01/09/2011 – 28/02/2014

Objective: In previous research, the team measured the amounts of substances called microRNAs (miRNAs) in the blood of hundreds of people. These are tiny pieces of a substance similar to DNA, called RNA, and are thought to be important in telling cells which genes to switch on and which to switch off.

In people with type 2 diabetes, the miRNAs have a distinctive ‘fingerprint’ that may be a marker of blood vessel health. This project aims to determine if this is the case, and could therefore help scientists monitor or predict complications involving blood vessels in people with type 1 or type 2 diabetes.

Categories: Treat, Strategic Research Agreement, Complications