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JDRF clinical trials

If you would like to take part in research, here are some JDRF clinical trials that are recruiting now.


What is TrialNet?

TrialNet is an international network of academic institutions, healthcare professionals and scientists dedicated to preventing type 1 diabetes.

Type 1 Diabetes TrialNet logo.

Their Pathway to Prevention study is part-funded by JDRF, and is aiming to better our understanding of how type 1 diabetes develops.

Those who sign up will also be told if they are in the early stages of developing type 1 diabetes or at increased risk of developing the condition, and will be given monitoring and follow up care.

They may also be offered the opportunity to take part in clinical trials.

Can I take part?

The study is looking for siblings and family members of people who live with type 1 diabetes. To get involved, you must:

  • not have been diagnosed with type 1 diabetes

and must either:

  • be between the ages of 3 and 45 and have a parent, brother/sister, or child with type 1 diabetes
  • be between the ages of 3 and 20 and have an aunt/uncle, cousin, grandparent, niece/nephew, or half-brother/sister with type 1 diabetes

Participants will be asked to provide a blood sample as well as some additional health data. This information will be used by researchers to run analyses that could help find trends and commonalities in type 1 development.

How to get involved

Find out more about the study, and if you meet the participation criteria, on the TrialNet website:

Hypoglycaemia Awareness Restoration Programme (HARPdoc)

What is HARPdoc?

Professor Stephanie Amiel

Around 25% of people with type 1 diabetes have some level of impaired awareness of hypoglycaemia, leaving them vulnerable to having severe hypos. HARPdoc (Hypoglycaemia Awareness Restoration Programme) is a treatment programme, based on existing talking therapies, which is designed to restore this awareness.

Professor Stephanie Amiel is carrying out a clinical trial to test how effective HARPdoc is.

The participants will complete the therapy programme, which will be delivered by diabetes nurses and dietitians. Professor Amiel will then look at changes in behaviour and measure the difference in the number of severe hypo episodes participants experienced before and after the therapy programme.

Can I take part?

To test how effective HARPdoc is, Professor Amiel is recruiting participants with type 1 diabetes who are having trouble recognising hypos.

You must:

  • be over 18 years old
  • have lived with type 1 diabetes for more than four years
  • be experiencing problematic hypoglycaemia for at least a year

How to get involved

Full details can be found on, using the code NCT02940873 to find Prof. Amiel’s study

If you’re ready to get involved, contact the HARPdoc team at

Other trials

If you can’t take part in any of the trials listed above, there are other ways to find a trial you can join.

You could ask your healthcare team about any research studies happening in your local area, or use our type 1 trial finder tool.

You can also find more UK-based clinical trials by using the NHS’s Be Part of Research service, or look further afield by searching the website (run by the USA’s National Institutes of Health).

It is important to always talk to your healthcare team about any clinical trial you are considering getting involved in. They will be able to offer advice on the risks and benefits of taking part in a clinical trial.

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Type 1 diabetes trial finder

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Use our clinical trial finder tool to find trials relevant to you

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