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JDRF clinical trials

JDRF clinical trials that are recruiting now are shown below.


An international collaboration

The Pathway to Prevention study is part funded by JDRF, and is aiming to better our understanding of how Type 1 diabetes develops.

The study is looking for siblings and family members of people who live with type 1 diabetes. To get involved, you must:

•   be between the ages of 3 and 45 and have a parent, brother/sister, or child with type 1 diabetes
•   be between the ages of 3 and 20 and have an aunt/uncle, cousin, grandparent, niece/nephew, or half-brother/sister with T1D
•   have not been diagnosed with type 1 diabetes

Type 1 Diabetes TrialNet logo.

Participants will be asked to provide a blood sample as well as some additional health data. This information will be used by researchers to run analyses that could help find trends and commonalities in Type 1 development. Those who sign up will also be told if they are in the early stages of developing type 1 diabetes or at increased risk of developing the condition, and will be given monitoring and follow up care. They may also be offered the opportunity to take part in clinical trials.

Find out more about the study, and if you meet the participation criteria on the TrialNet website:

Hypoglycaemia Awareness Restoration Programme (HARPdoc)

Professor Stephanie Amiel, King’s College London

Professor Stephanie Amiel

Prof. Amiel will be carrying out a clinical trial to test a new Hypoglycaemia Awareness Restoration Programme (HARPdoc). HARPdoc is a treatment programme based on existing talking therapies, which has been designed to improve management of hypo unawareness.

To test how effective HARPdoc is, Prof. Amiel is recruiting participants with type 1 diabetes who are having trouble recognising hypos. The participants will complete the therapy programme, which will be delivered by diabetes nurses and dietitians. Prof. Amiel will then look at changes in behaviour and measure the difference in the number of severe hypo episodes participants experienced before and after the therapy programme.

Criteria for taking part include:

  • Over 18 years old
  • Having lived with type 1 diabetes for more than four years
  • Experiencing problematic hypoglycaemia for at least a year

How to get involved in this clinical trial:

Full details can be found on, using the code NCT02940873 to find Prof. Amiel’s study

If you’re ready to get involved, contact the HARPdoc team at